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25周年紀念號登場！

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Caroline Tam

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Natalie Lau: The 20-Year-Old Culinary Genius Reinventing Hong Kong's Street Food Scene

Earlier this month, Dr. Eva Ramón Gallegos, a researcher at the Instituto Politécnico Nacional (IPN) in Mexico City, announced promising results from her long-term research on treating human papillomavirus (HPV) and cervical cancer. Using an innovative, non-invasive method called photodynamic therapy (PDT), her team reported success in eliminating HPV and pre-cancerous lesions in a small group of women, a development that could reshape approaches to cervical cancer prevention and treatment.<figure class="image"><img src="https://prd-cdn.jessicahk.com/6_XNVBXSZHJDN_5_GPXM_5_IQ_2_AKGUY_98b58dfff7.avif" alt="6XNVBXSZHJDN5GPXM5IQ2AKGUY.avif"><figcaption>Photo from El Universal</figcaption></figure>HPV and Its ImpactHPV is the most common sexually transmitted infection worldwide. According to research from the National Institutes of Health, approximately 80% of women will encounter the virus at some point in their lives. While most HPV infections clear up on their own, certain high-risk strains can persist and lead to cervical cancer, a major global health concern—particularly in Mexico, where cervical cancer is the second-leading cause of cancer death among women, highlighting the urgency of effective interventions.Currently, there is no existing cure for HPV. Prevention hinges on vaccination (recommended for children and young adults) and regular screening, while treatments focus on managing symptoms like genital warts or removing precancerous lesions. These interventions, such as cryotherapy or surgical excision, can be invasive and carry risks, underscoring the demand for safer, more targeted options.Photodynamic TherapyDr. Eva Ramón Gallegos has spent over 20 years refining photodynamic therapy, a technique that uses light and a photosensitizing agent to destroy abnormal cells while sparing healthy tissue. Unlike chemotherapy, which affects both diseased and healthy cells, PDT offers precision by targeting only damaged areas.In her method, a drug called delta-aminolevulinic acid is applied to the cervix. This compound is absorbed by cells and converted into protoporphyrin IX, a light-sensitive substance that accumulates more in abnormal cells than in normal ones. After a period of time is allowed for the drug to clear from healthy tissue, a specific wavelength of light is applied, activating the protoporphyrin IX to produce reactive oxygen species that destroy the targeted cells.<figure class="image"><img src="https://prd-cdn.jessicahk.com/national_institute_of_allergy_and_infectious_diseases_DT_Ldex_F73_Us_unsplash_32c4ca49ab.jpg" alt="national-institute-of-allergy-and-infectious-diseases-DTLdexF73Us-unsplash.jpg"><figcaption>Photo from Unsplash</figcaption></figure>Reported ResultsDr. Ramón Gallegos’s study involved 29 women and yielded impressive, though preliminary, outcomes:<ul><li>85% Cure Rate for HPV Alone: Among women with HPV but no cervical lesions, 85% tested negative for the virus post-treatment.</li><li>85% Success with HPV and Lesions: In women with both HPV and pre-cancerous lesions, 85% saw both the virus and lesions eliminated.</li><li>42% Efficacy Without HPV: For women with lesions but no detectable HPV, the treatment cleared lesions in about 42% of cases.</li><li>100% Success with Higher Dosage: Doubling the delta-aminolevulinic acid concentration reportedly eradicated HPV in 100% of women with the virus but no lesions.</li></ul>These results suggest PDT could not only treat HPV infections but also stop progression to cervical cancer by addressing early-stage abnormalities.Context and LimitationsThe findings build on a previous IPN report from 2019, where Dr. Eva Ramón Gallegos first announced similar success with PDT in a larger cohort of over 400 women. However, peer-reviewed publications confirming these results—particularly the February 2025 announcement—are not yet available, suggesting the need for caution until further studies are conducted. The small sample size of 29 women in this study also limits broader conclusions.Photodynamic therapy itself is an established technique, but its application to HPV is new. The U.S. National Cancer Institute notes that PDT is limited to surface-level conditions because light cannot penetrate deeply into tissue. A 2023 study in Medicine on PDT for other conditions also reported mild side effects such as burns, scarring, and temporary light sensitivity, consistent with Dr. Ramón Gallegos's findings of minimal adverse effects compared to surgery or chemotherapy.<figure class="image"><img src="https://prd-cdn.jessicahk.com/ZUOFFVSF_65_DMXEGQ_57_ILX_5_KW_6_U_38992b7fe1.avif" alt="ZUOFFVSF65DMXEGQ57ILX5KW6U.avif"><figcaption>Photo from El Universal</figcaption></figure>A Step Toward a Cure?Dr. Eva Ramón Gallegos’ research proves the potential of photodynamic therapy to transform women’s health. Though her work suggests a hopeful future, rigorous follow-up and long-term studies are required to confirm whether HPV clearance is sustainable, as well as to assess the rates of recurrence. If validated, Mexico could emerge as a leader in HPV treatment and reduce the global burden of cervical cancer and, with further development and peer-review, could provide a certified, non-invasive solution to HPV—potentially saving millions of lives in the future.

Dr. Eva Ramón Gallegos: Pioneering Solutions for HPV and Women's Health

近年，環保是社會非常重視的一大課題。 為拯救地球的損耗，嘉士伯集團數年前已高瞻遠瞩，發佈將研發世界首個「紙製」啤酒瓶的理念，並於今天假丹麥哥本哈根舉行的 C40世界市長峰會中更新其設計進 度 。這個名為 Green Fibre Bottle的啤酒瓶破天荒以 100％生物源的可持續木纖維製成，可完全回收。此項設計可謂是啤酒行業邁向綠色環保的一大突破。
<img src="https://prd-cdn.jessicahk.com/files/Green Fibre Bottle prototypes.jpg" title="顛覆啤酒業！嘉士伯全球首枝「紙製」啤" class="paragraph-image" alt="顛覆啤酒業！嘉士伯全球首枝「紙製」啤"/>
會上，嘉士伯集團於公佈兩款全球首個以 「紙製」並可盛載啤酒的啤酒瓶設計原型，同時宣佈其透過 紙瓶技術發展可持續包裝的嶄新意念，得到其他國際領先企業的認同，並加入此創新構思的研究。這不單是嘉士伯創新發展可持續包裝技術的延續，更是其「 攜手邁向零排放 」可持續發展計劃 的關鍵 承諾實現旗下啤酒廠 「 零碳排放 」以及於 2030年前將碳排放減少 30%。
<img src="https://prd-cdn.jessicahk.com/files/Green Fibre Bottle prototype close up.jpg" title="顛覆啤酒業！嘉士伯全球首枝「紙製」啤" class="paragraph-image" alt="顛覆啤酒業！嘉士伯全球首枝「紙製」啤"/>
嶄新設計原型 
這次公佈的兩款啤酒瓶設計原型均採用可持續木纖維製成，並可完全回收利用，而內部則分別使用了rPET 薄膜及100％生物源PEF 薄膜，讓瓶子能盛裝啤酒。此兩款原型將進行阻隔技術測試，務求能實現嘉士伯期望製造無聚合物及100％生物基瓶的最終目標。

square-46808_Green-Fibre-Bottle-prototype-with-Carlsberg-pilsner1.jpg

顛覆啤酒業！嘉士伯全球首枝「紙製」啤

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